Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT1F-G protein complex

  • Cell Res. 2021 Sep;31(9):1036-1038. doi: 10.1038/s41422-021-00527-4.
Sijie Huang  #  1  2  3 ,  Peiyu Xu  #  1  2 ,  Yangxia Tan  #  1  2 ,  Chongzhao You  1  2 ,  Yumu Zhang  1  2  3 ,  Yi Jiang  4  5 ,  H Eric Xu  6  7  8
Affiliations
  • 1. The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • 2. University of Chinese Academy of Sciences, Beijing, China.
  • 3. School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • 4. The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. [email protected].
  • 5. University of Chinese Academy of Sciences, Beijing, China. [email protected].
  • 6. The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. [email protected].
  • 7. University of Chinese Academy of Sciences, Beijing, China. [email protected].
  • 8. School of Life Science and Technology, ShanghaiTech University, Shanghai, China. [email protected].
  • # Contributed equally.
PMID: 34239069 DOI: 10.1038/s41422-021-00527-4