EDTA-OH
Based on 1 Customer Validation
EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper. EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils. EDTA-OH is able to cross brain-blood barrier.
For research use only. We do not sell to patients.
- Purity: 99.48%
- CAS No.: 150-39-0
- Formula: C10H18N2O7
- Molecular Weight:278.26
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Aluminium overload in wistar rats[3]
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Dosage:50 mg/kg
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Administration:i.p. for 5 days
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Result:Inhibited GST activity, reduced the concentration of aluminium in blood and brain.
Chemical Information
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CAS No. 150-39-0
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Appearance Solid
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Molecular Weight 278.26
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Formula C10H18N2O7
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Color White to off-white
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SMILES
O=C(O)CN(CCO)CCN(CC(O)=O)CC(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 17.5 mg/mL (62.89 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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Handling Instructions (2659 KB)
References
[1]. Li X, Zhang Z, et al., Complexation of Light Trivalent Lanthanides with N-(2-Hydroxyethyl)ethylenediamine-N,N',N'-triacetic Acid in Aqueous Solutions: Thermodynamic Analysis and Coordination Modes. Inorg Chem. 2019 Nov 18;58(22):15618-15628. [Content Brief]
[2]. Chen H, et al., EDTA and HEDTA effects on Cd, Cr, and Ni uptake by Helianthus annuus. Chemosphere. 2001 Oct;45(1):21-8. [Content Brief]
[3]. Flora SJ, et al., Aluminum-induced oxidative stress in rat brain: response to combined administration of citric acid and HEDTA. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Mar;134(3):319-28. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.5938 mL | 17.9688 mL | 35.9376 mL | 89.8440 mL |
| 5 mM | 0.7188 mL | 3.5938 mL | 7.1875 mL | 17.9688 mL | |
| 10 mM | 0.3594 mL | 1.7969 mL | 3.5938 mL | 8.9844 mL | |
| 15 mM | 0.2396 mL | 1.1979 mL | 2.3958 mL | 5.9896 mL | |
| 20 mM | 0.1797 mL | 0.8984 mL | 1.7969 mL | 4.4922 mL | |
| 25 mM | 0.1438 mL | 0.7188 mL | 1.4375 mL | 3.5938 mL | |
| 30 mM | 0.1198 mL | 0.5990 mL | 1.1979 mL | 2.9948 mL | |
| 40 mM | 0.0898 mL | 0.4492 mL | 0.8984 mL | 2.2461 mL | |
| 50 mM | 0.0719 mL | 0.3594 mL | 0.7188 mL | 1.7969 mL | |
| 60 mM | 0.0599 mL | 0.2995 mL | 0.5990 mL | 1.4974 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.