MAO-B-IN-10
MAO-B-IN-10 (compound 4f) is a potent, selective, BBB-penetrated MAO-B (monoamine oxidase-B) inhibitor, with IC50 of 5.3 μM. MAO-B-IN-10 can inhibit (58.2%) and disaggregate (43.3%) self-mediated Aβ (amyloid β) aggregation. MAO-B-IN-10 can be use for Alzheimer’s disease research.
For research use only. We do not sell to patients.
- CAS No.: 2376710-36-8
- Formula: C23H26N2O4
- Molecular Weight:394.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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MAO-B 5.3 ± 0.22 μM (IC50) |
MAO-A 15.9 ± 0.1 μM (IC50) |
Chemical Information
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CAS No. 2376710-36-8
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Molecular Weight 394.46
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Formula C23H26N2O4
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SMILES
CCN(C(OC1=C(C=C(C=C1)/C=C/C(N2CCC3=C(C2)C=CC=C3)=O)OC)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)