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Cat. No.: HY-146051

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Antitubercular agent-18

Antitubercular agent-18 (Compound 9a) is an antitubercular agent with MIC values of 2, 2, 2 and 128 µg/ml against M. tuberculosis H37Rv, Spec. 192, Spec 210 and Spec. 800, respectively. Antitubercular agent-18 shows highly selective antimycobacterial effects.

For research use only. We do not sell to patients.

CAS No.: 1308272-99-2
Formula: C₁₄H₁₂BrN₅O
Molecular Weight:346.18

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Antitubercular agent-18 Chemical Structure

CAS No.: 1308272-99-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HaCaT	IC₅₀	131.26 μM Compound: 9a	Cytotoxicity against human HaCaT cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human HaCaT cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 31753514]
V79	IC₅₀	212.46 μM Compound: 9a	Cytotoxicity against Chinese Hamster V79 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against Chinese Hamster V79 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 31753514]

Chemical Information

CAS No. 1308272-99-2
Molecular Weight 346.18
Formula C₁₄H₁₂BrN₅O
SMILES

COC1=CC=C(N2N=NN=C2NC3=CC=C(Br)C=C3)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Szulczyk D, et al. Development of (4-methoxyphenyl)-1H-tetrazol-5-amine regioisomers as a new class of selective antitubercular agents. Eur J Med Chem. 2020 Jan 15;186:111882. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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