SYNTi
Based on 1 Customer Validation
SYNTi is a PDZ domain inhibitor targeting the syndecan/syntenin protein-protein Interaction. SYNTi exhibits an IC50 value of 400 nM and ligand efficiency (LE) value of 0.24. SYNTi can be used for breast cancer research.
For research use only. We do not sell to patients.
- Formula: C28H24BrFN2O5
- Molecular Weight:567.40
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
SYNTi (1-100 μM) significantly affects the migration speed and Euclidean distance of MDA-MB-231 cells[1].
SYNTi is not toxic at concentrations up to 100 μM in wild-type MDA-MB-231 breast carcinoma cells and in MDA-MB-231 cells with syntenin-KO[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 567.40
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Formula C28H24BrFN2O5
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SMILES
O=C1N(CC2=CC(Br)=CC=C21)[C@H](C(N[C@H](C(O)=O)C)=O)CC3=CC=C(C=C3)C4=CC(C(C)=O)=CC=C4F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)