Jatrophane diterpenoids from Euphorbia peplus

  • Phytochemistry. 1999 Jul;51(5):673-7. doi: 10.1016/s0031-9422(99)00088-6.
J Hohmann  1 ,  A Vasas ,  G Günther ,  G Dombi ,  G Blazsó ,  G Falkay ,  I Máthé ,  G Jerkovich
Affiliations
  • 1. Department of Pharmacognosy, Albert Szent-Györgyi Medical University, Szeged, Hungary.
PMID: 10392470 DOI: 10.1016/s0031-9422(99)00088-6
Abstract

From the pro-inflammatory active extract of Euphorbia peplus, a new diterpene polyester (1) based on the jatrophane skeleton was isolated together with the known compounds 2-5. The irritant activities of some jatrophane diterpenes (2, 3 and 6-9) were also investigated: only compound 2 was found to exert a weak pro-inflammatory activity on mouse ear.

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