hflC Protein, E.coli
The hflC protein cooperates with HflK to centrally regulate the stability of the phage lambda cII protein and affect the lysogenization frequency. HflC and HflK cooperate to form HflKC, which inhibits the SecY degradation activity of FtsH and may contribute to overall membrane protein quality control. hflC Protein, E.coli is the recombinant E. coli-derived hflC protein, expressed by E. coli , with tag free.
- Species: E.coli
- Source: E. coli
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Biological Activity
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Product Properties
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Biological Activity
The hflC protein cooperates with HflK to centrally regulate the stability of the phage lambda cII protein and affect the lysogenization frequency. HflC and HflK cooperate to form HflKC, which inhibits the SecY degradation activity of FtsH and may contribute to overall membrane protein quality control. hflC Protein, E.coli is the recombinant E. coli-derived hflC protein, expressed by E. coli , with tag free.
The hflC Protein, in collaboration with HflK, plays a pivotal role in regulating the stability of the phage lambda cII protein, thereby exerting control over the lysogenization frequency of phage lambda. Beyond its involvement in phage dynamics, HflC, in conjunction with HflK, forms a complex known as HflKC, originally referred to as HflA. This complex interacts with FtsH, inhibiting its SecY-degrading activity and potentially contributing to the quality control of integral membrane proteins. The interaction between HflKC and FtsH is stimulated by ATP, emphasizing the dynamic nature of this regulatory mechanism. Additionally, HflKC engages with YccA, further expanding its network of interactions and underscoring its multifaceted role in cellular processes.
Technical Parameters
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Species E.coli
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Source E. coli
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Tag Tag Free
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Accession
P0ABC4 (M1-R334)
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Gene ID86861431
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Molecular Construction
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N-term
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hflC (M1-R334)
Accession # P0ABC4 -
C-term
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Protein Length
Full Length
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Synonyms
hflC; Modulator of FtsH protease HflC
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AA Sequence
MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNKPLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSRYYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSAGTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTEVSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGDAEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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