ITM2A Protein, Mouse (Cell-Free, His)

The ITM2A protein is expressed in the mandibular condyle, bone, and hair follicles, and is particularly robust in osteogenic tissues, suggesting involvement in bone development and maintenance, emphasizing its role in osteogenesis. Expression in hair follicles suggests additional functions in skin-related processes. ITM2A Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived ITM2A protein, expressed by E. coli Cell-free, with N-10*His labeled tag. The total length of ITM2A Protein, Mouse (Cell-Free, His) is 263 a.a., with molecular weight of 31.2 kDa.

For research use only. We do not sell to patients.
  • Species: Mouse
  • Source: E. coli Cell-free
  • Biological Activity
  • Product Properties
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Biological Activity

Description

The ITM2A protein is expressed in the mandibular condyle, bone, and hair follicles, and is particularly robust in osteogenic tissues, suggesting involvement in bone development and maintenance, emphasizing its role in osteogenesis. Expression in hair follicles suggests additional functions in skin-related processes. ITM2A Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived ITM2A protein, expressed by E. coli Cell-free, with N-10*His labeled tag. The total length of ITM2A Protein, Mouse (Cell-Free, His) is 263 a.a., with molecular weight of 31.2 kDa.

Background

ITM2A protein exhibits expression in mandibular condyles, bone, and hair follicles, with particularly robust expression in osteogenic tissues such as neonatal calvaria, paws, tail, and skin. The presence of ITM2A in these specific tissues suggests its potential involvement in skeletal development and maintenance, emphasizing its role in osteogenesis. Furthermore, its expression in hair follicles hints at additional functions in skin-related processes. The distinct spatial expression pattern of ITM2A underscores its significance in various tissues, implicating its participation in molecular events related to bone development and homeostasis, as well as potential contributions to skin and hair biology.

Technical Parameters

  • Species Mouse
  • Source E. coli Cell-free
  • Tag N-10*His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • 10*His
    • ITM2A (M1-E263)
      Accession # Q61500
    • C-term
  • Synonyms

    Integral membrane protein 2A; Protein E25; Itm2a; E25; Itm2

  • AA Sequence

    MVKIAFNTPTAVQKEEARQDVEALVSRTVRAQILTGKELRVVPQEKDGSSGRCMLTLLGLSFILAGLIVGGACIYKYFMPKSTIYHGEMCFFDSEDPVNSIPGGEPYFLPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMTPKNLVELFGKLASGKYLPHTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE

  • Predicted Molecular Mass

    31.2 kDa

  • Purity

    ≥ 85%, as determined by reducing SDS-PAGE.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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