2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. Risimtinib

Risimtinib (Risimtinibum) is a FGFR1 inhibitor with an IC50 of 2.1 nM. Risimtinib inhibits the proliferation of FGFR1-positive cancer cells. Risimtinib is used for the research of myeloid leukemia.

For research use only. We do not sell to patients.

Risimtinib

Risimtinib Chemical Structure

CAS No. : 2126751-11-7

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Risimtinib Related Antibodies

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Description

Risimtinib (Risimtinibum) is a FGFR1 inhibitor with an IC50 of 2.1 nM. Risimtinib inhibits the proliferation of FGFR1-positive cancer cells. Risimtinib is used for the research of myeloid leukemia[1].

IC50 & Target[1]

FGFR1

2.1 nM (IC50)

In Vitro

Risimtinib (compound 19a) potently inhibits purified FGFR1 kinase activity with an IC50 of 2.1 nM[1].
Risimtinib inhibits the proliferation of FGFR1-translocated KG-1 leukemia cells with an IC50 of 14.9 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Risimtinib Related Antibodies
Molecular Weight

509.60

Formula

C30H31N5O3
CAS No.
SMILES

CNC(C1=CC=CC2=C1C=CC(OC3=CC=NC(NC(C4=CC=C(N5C[C@H](N[C@H](C5)C)C)C=C4)=O)=C3)=C2)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Risimtinib Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Risimtinib2126751-11-7RisimtinibumFGFRFibroblast growth factor receptorFGFR1-translocated KG-1 leukemia cellsmyeloid leukemiaFGFR1FGFR1-positive cancer cellsInhibitorinhibitorinhibit

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