3'-ONH2-dATP
3'-ONH2-dATP is a 3'-O-blocked reversible terminator deoxynucleotide triphosphate. 3'-ONH2-dATP stops DNA polymerization after single-nucleotide addition to an initiator strand, and its 3'-ONH2 blocking group can be removed to restore a free 3'-OH for subsequent extension.
For research use only. We do not sell to patients.
- CAS No.: 1220515-87-6
- Formula: C10H17N6O12P3
- Molecular Weight:506.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
3'-ONH2-dATP (0.25 mM; 20 min) led to wild-type ZaTdT exhibiting negligible catalytic activity for 3'-ONH2-dATP, with no detectable incorporation into CT-terminated synthetic DNA initiator strands under tested conditions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1220515-87-6
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Molecular Weight 506.20
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Formula C10H17N6O12P3
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SMILES
O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C=NC3=C2N=CN=C3N)C[C@@H]1ON)(O)=O)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3'-ONH2-dATP Related Classifications
HY-178531 Related Classifications
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