Pdia6 - protein disulfide isomerase associated 6 Gene

Also Known as P5; CaBP5; Txndc7; 1700015E05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71853

Summary

Enables protein-disulfide reductase activity. Involved in negative regulation of IRE1-mediated unfolded protein response. Part of endoplasmic reticulum chaperone complex. Is expressed in embryo; liver; lung epithelium; and pancreas epithelium. Orthologous to human PDIA6 (protein disulfide isomerase family A member 6). [provided by Alliance of Genome Resources, Apr 2022]

Pdia6 Products (1)

mRNA Protein Name
NM_027959.4 NP_082235.2 protein disulfide-isomerase A6 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein-disulfide reductase activity IMP
IMP: Inferred from mutant phenotype
24508390 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of IRE1-mediated unfolded protein response IMP
IMP: Inferred from mutant phenotype
24508390 MGI
Cellular Component GO Annotation Evidence References Source
part of endoplasmic reticulum chaperone complex IDA
IDA: Inferred from direct assay
12475965 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein disulfide-isomerase A6

  • protein disulfide isomerase-related protein

  • thioredoxin domain containing 7

  • thioredoxin domain-containing protein 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122895 E64FC26 98.48% Unkown
HY-122895A (E/Z)-E64FC26 99.80% Unkown
HY-170655 PDI-IN-4 Inhibitor / Unkown
HY-P11857 Alkyne-GRWHPM-CONH-NH-CMK Inhibitor / Unkown
HY-RS10271 PDIA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17990 Pdia6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24461 Pdia6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdia6 NCBI NCBI:10130