179 Results for "

lambda

" in MedChemExpress (MCE) Product Catalog:
Products (179)

179 Results for "lambda" in MCE Product Catalog:

Cat. No.: HY-P990446
Synonyms: DISC0280

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

The Anti-IL-15 Antibody (DISC0280) is a CHO-expressed human antibody that targets IL-15. The Anti-IL-15 Antibody (DISC0280) has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-IL-15 Antibody (DISC0280) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990483
Synonyms: PAR650097

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-PAR2 Antibody (PAR650097) is a CHO-expressed human antibody that targets PAR2. Anti-PAR2 Antibody (PAR650097) has a huIgG1 heavy chain and huλ light chain, with a predicted molecular weight (MW) of 144.1 kDa. The isotype control for Anti-PAR2 Antibody (PAR650097) can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P99867
CAS No.: 1204390-13-5
Synonyms: MEDI 573

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Dusigitumab is a fully human IgG2λ monoclonal antibody that targets IGF-1 and IGF-2 with picomolar binding affinity. Dusigitumab blocks IGF-1 and IGF-2-induced phosphorylation of IGF-1R as well as activation of IR-A, thereby inhibiting the activation of downstream signaling pathways. Dusigitumab is applicable to research related to advanced solid tumors and hormone receptor-positive metastatic breast cancer .
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Cat. No.: HY-P990153

Research Areas:  

Inflammation/Immunology

Anti-Mouse TIM-2 Antibody (RMT2-29) is a rat-derived Ig2a λ type antibody inhibitor, targeting to mouse TIM-2. Anti-Mouse TIM-2 Antibody (RMT2-29) reacts with mouse T cell immunoglobulin and mucin domain 2 (TIM-2) and blocks TIM-2 signaling. Anti-Mouse TIM-2 Antibody (RMT2-29) can be used for the research of immunology.
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Cat. No.: HY-P990223
Anti-Mouse IL-15 Antibody (AIO.3) is a rat-derived IgG2a λ type antibody inhibitor, targeting to mouse IL-15. Anti-Mouse IL-15 Antibody (AIO.3) can neutralize IL-15. Anti-Mouse IL-15 Antibody (AIO.3) can be used for the researches of cancer, infection and inflammation, such as hepatitis virus infection and esophagitis .
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Cat. No.: HY-P990329

Research Areas:  

Inflammation/Immunology

Anti-Albumin Antibody is a monoclonal IgG1 antibody targeting human serum albumin (HSA). Anti-Albumin Antibody binds to immobilized Human HSA-hFc, with an EC50 of 0.04661 μg/mL in ELISA assays using 2 μg/mL HSA-hFc. Anti-Albumin Antibody is applicable for human serum albumin detection and research related to antigen-antibody interactions. The corresponding isotype control is: Human IgG1 lambda2, Isotype Control (HY-P990096) .
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Cat. No.: HY-P76400
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Interferon alpha-14; Interferon alpha-H; LeIF H; Interferon lambda-2-H; IFNA14
Species:  
Source:  
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Cat. No.: HY-P77390
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Interferon alpha-14; Interferon alpha-H; LeIF H; Interferon lambda-2-H; IFNA14
Species:  
Source:  
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Cat. No.: HY-169217
Target:  

Cytochrome P450

Research Areas:  

Cancer

CYP3A4-IN-4 (compound Δ,Λ-3), a Ru(II) Ir(III) Conjugate, is a photoactive inhibitor of the major human drug metabolizing enzyme CYP3A4. CYP3A4-IN-4 containing the [Ru(tpy)(Me2bpy)] photocaging group showed an IC50 of 2.2 μM for inhibition of microsomal CYP3A4 under light conditions (λirr=530 nm, tirr=15 min) .
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Cat. No.: HY-P990009
CAS No.: 2649854-92-0
Synonyms: NIS-793

Research Areas:  

Cancer

Nisevokitug (NIS-793) is a humanized IgG2λ monoclonal antibody and an inhibitor of the TGF-β signaling pathway. Nisevokitug blocks the binding of TGF-β to the membrane-bound TGF-βR1/TGF-βR2 receptors, inhibits both Smad-dependent and Smad-independent downstream cascade signaling, downregulates fibrosis-related genes, and reverses the TGF-β-mediated immunosuppressive microenvironment. Nisevokitug can be used in the research of diseases such as pancreatic ductal adenocarcinoma, colorectal cancer, myelofibrosis, and myelodysplastic syndrome .
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Cat. No.: HY-P990469
Synonyms: TA136

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

The Anti-MPL/TPOR/CD110 Antibody (TA136) is a CHO-expressed humanized antibody that targets MPL/TPOR/CD110. The Anti-MPL/TPOR/CD110 Antibody (TA136) features a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-MPL/TPOR/CD110 Antibody (TA136) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P99551
CAS No.: 1374419-41-6
Synonyms: KBSA301; AR-301

Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Tosatoxumab (AR-301; KBSA301) is a human immunoglobulin G1 monoclonal antibody that specifically neutralizes alpha-toxin (alpha-hemolysin; Hla) of S. aureus. Tosatoxumab binds to an N-terminal epitope of alpha-toxin, thereby preventing functional toxin pore oligomerisation. Tosatoxumab has the potential for passive immunotherapy in the S. aureus pneumonia as an adjunctive therapy to standard antibiotic agent. Recommend Isotope Control: Human IgG1 lambda1, Isotype Control (HY-P99992) .
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Cat. No.: HY-P82886
Synonyms: PRKCI; DXS1179E; Protein kinase C iota type; PRKCZ; PKC2; Protein kinase C zeta type

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

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Cat. No.: HY-P990381

Target:  

c-Fms

Research Areas:  

Inflammation/Immunology

The Anti-CSF2/GM-CSF Antibody is a CHO-expressed human antibody that targets CSF2/GM-CSF. The Anti-CSF2/GM-CSF Antibody has a huIgG1-type heavy chain and a huλ-type light chain, with a predicted molecular weight (MW) of 145.02 kDa. The isotype control for the Anti-CSF2/GM-CSF Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990395

Target:  

CXCR

Research Areas:  

Inflammation/Immunology

Anti-CXCR4/CD184 Antibody is a CHO-expressed human antibody that targets CXCR4/CD184. The Anti-CXCR4/CD184 Antibody has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-CXCR4/CD184 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990537

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

The Anti-VCAM1/CD106 Antibody is a humanized antibody expressed in CHO cells, targeting VCAM1/CD106. The Anti-VCAM1/CD106 Antibody has a huIgG2 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 143.4 kDa. For the isotype control of the Anti-VCAM1/CD106 Antibody, please refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P99521
CAS No.: 2138442-13-2
Synonyms: XmAb14045

Target:  

CD3

Research Areas:  

Inflammation/Immunology Cancer

Vibecotamab (XmAb14045) is a potent bispecific antibody targeting both CD123 and CD3. Vibecotamab targets T cell-mediated killing of CD123-expressing cells, regardless of T cell antigen specificity. Vibecotamab is a full length immunoglobulin molecule. Vibecotamab can be studied in research for diseases such as Myelodysplastic syndrome and acute myeloid leukemia. Recommend Isotype Control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3 .
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Cat. No.: HY-P82886A
Synonyms: PRKCI; DXS1179E; Protein kinase C iota type; PRKCZ; PKC2; Protein kinase C zeta type

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

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Cat. No.: HY-P991640
Synonyms: BIIB015 antibody

Target:  

ADC Antibodies

Research Areas:  

Cancer

Anti-TDGF1 antibody (huB3F6) (BIIB015 antibody) is a CHO-expressed human antibody that targets TDGF1. Anti-TDGF1 antibody has huIgG1 heavy chain and huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-TDGF1 antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Anti-TDGF1 antibody (huB3F6) can be used for synthesis of ADCs .
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Cat. No.: HY-P992181
Synonyms: MEDI1116; VIB-1116; HZN-1116

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

AMG-329 (MEDI1116) is a human immunoglobulin G1λ monoclonal antibody targeting FLT3L. AMG-329 selectively binds to FLT3L, blocks FLT3L-FLT3 interaction, neutralizes soluble and cell-bound human FLT3L activity. AMG-329 reduces circulating relative proportions of plasmacytoid dendritic cells, conventional dendritic cells, and classical monocytes. AMG-329 does not induce antibody dependent cellular cytotoxicity. AMG-329 can be used for the research of sjögren’s disease .
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