1. Immunology/Inflammation
  2. Interleukin Related
  3. Anti-IL-15 Antibody (DISC0280)

Anti-IL-15 Antibody (DISC0280)  (Synonyms: DISC0280)

Cat. No.: HY-P990446 Purity: 99.35%
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The Anti-IL-15 Antibody (DISC0280) is a CHO-expressed human antibody that targets IL-15. The Anti-IL-15 Antibody (DISC0280) has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-IL-15 Antibody (DISC0280) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

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Description

The Anti-IL-15 Antibody (DISC0280) is a CHO-expressed human antibody that targets IL-15. The Anti-IL-15 Antibody (DISC0280) has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-IL-15 Antibody (DISC0280) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

Isotype

Human IgG1 kappa

Recommend Isotype Controls
Species Reactivity

Human

IC50 & Target

IL-15

Gene ID

3600  [NCBI]

Accession

P40933-1

Application

ELISA, FACS, Functional assay

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Molecular Weight

145.12 kDa

Appearance

Liquid

Color

Colorless to light yellow

Shipping

Shipping with dry ice.

Formulation

Please refer to the lot-specific COA for specific buffer information.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Biological Activity
  • Immobilized IL-15 Protein, Human, HY-P7034 can bind Anti-IL-15 Antibody (DISC0280). The EC50 for this effect is 47.74 ng/mL.
  • Anti-IL-15 Antibody (HY-P990446) neutralizes Recombinant Human IL-15 (HY-P7034) induced proliferation in the Mo7e cell line. The Neutralization Dose (ND50) for this effect is 0.026 μg/mL in the presence of 10 ng/mL Recombinant Human IL-15.
Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Anti-IL-15 Antibody (DISC0280)
Cat. No.:
HY-P990446
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