2 Results for "

2-Oxoadamantane

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "2-Oxoadamantane" in MCE Product Catalog:

Cat. No.: HY-Y0421
CAS No.: 700-58-3
Synonyms: 2-Adamantone; 2-Oxoadamantane
Target:  

11β-HSD

Research Areas:  

Others

Adamantanone (2-Adamantone; 2-Oxoadamantane) serves as a substrate for some alcohol dehydrogenases and also acts as a probe for characterizing substrate-binding pockets. Adamantanone can be reduced by 3α-hydroxysteroid dehydrogenase and 3β-17β-hydroxysteroid dehydrogenase derived from Pseudomonas testosteroni, and it can fit into the conformationally flexible substrate-binding pockets of these enzymes that undergo substrate-induced fit .
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Cat. No.: HY-184832
CAS No.: 1246751-68-7
Synonyms: Peptide 021
Target:  

Amyloid-β Tau Protein

Research Areas:  

Neurological Disease

P021 (Peptide 021) is an orally active, blood-brain barrier penetrant neurotrophic/neurogenic pentapeptide derived from the most active region of ciliary neurotrophic factor (CNTF). P021 competitively inhibits leukemia inhibitory factor (LIF) and promotes BDNF transcription. P021 targets neurogenesis and synaptic plasticity. P021 prevents neurodegeneration, Amyloid-β pathology, tau protein pathology and cognitive deficits, rescues episodic memory impairment and reduces mortality in 3xTg-AD mice. P021 is applicable to the research of Alzheimer's disease .
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