700-58-3
700-58-3
Chemical Structure
Adamantanone
Synonym(s): 2-Adamantone; 2-Oxoadamantane
- No. CAS: 700-58-3
- Formula:C10H14O
- Molecular Weight:150.22
IUPAC Name: (1r,3r,5r,7r)-adamantan-2-one
InChIKey: IYKFYARMMIESOX-SPJNRGJMSA-N
SMILES: O=C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Biological Activity: Adamantanone (2-Adamantone; 2-Oxoadamantane) serves as a substrate for some alcohol dehydrogenases and also acts as a probe for characterizing substrate-binding pockets. Adamantanone can be reduced by 3α-hydroxysteroid dehydrogenase and 3β-17β-hydroxysteroid dehydrogenase derived from Pseudomonas testosteroni, and it can fit into the conformationally flexible substrate-binding pockets of these enzymes that undergo substrate-induced fit[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Adamantanone | 99.79% | Adamantanone (2-Adamantone; 2-Oxoadamantane) serves as a substrate for some alcohol dehydrogenases and also acts as a probe for characterizing substrate-binding pockets. Adamantanone can be reduced by 3α-hydroxysteroid dehydrogenase and 3β-17β-hydroxysteroid dehydrogenase derived from Pseudomonas testosteroni, and it can fit into the conformationally flexible substrate-binding pockets of these enzymes that undergo substrate-induced fit. | ||||||||||||||||||||
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1-Adamantaneethanol | 99.82% | 1-Adamantaneethanol is an allele-selective MHC II class molecule loading enhancer (MHC loading enhancer, MLE) that enhances peptide loading and ligand exchange of HLA-DR molecules. 1-Adamantaneethanol targets the polymorphic P1 pocket of HLA-DR molecules and preferentially acts on HLA-DR subtypes with Gly at position β86, thereby stabilizing the peptide-receptor conformation and accelerating antigen loading. 1-Adamantaneethanol can be used in studies related to MHC II antigen presentation, peptide vaccines, adaptive immunity and tumor immunity. |
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Adamantane-Butyl alcohol | Adamantane-Butyl alcohol is a selective and persistent degrader targeting the CDK8-cyclin C complex. Adamantane-Butyl alcohol is the linker for LL-K8-22 (PROTAC CDK8-cyclin C, HY-149209) and HyT. | |||||||||||||||||||||
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1-Adamantylcarbinyl iodide | 95.0% | 1-Adamantylcarbinyl iodide is a drug intermediate for synthesis of various active compounds. | ||||||||||||||||||||
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Idramantone | 98.0% | Idramantone (Kemantane, 5-Hydroxy-2-adamantanone) is an adamantane-based immunomodulator. Idramantone increases the activity of T helper cells by 1.5 to 2-fold, but exerts no significant effect on the functional activity, induction or accumulation of antigen-specific T suppressor cells. Idramantone serves as a key intermediate for the synthesis of various adamantane derivatives, and can be produced via the regioselective oxidation of 2-adamantanone catalyzed by P450cam monooxygenase, a process that relies on an NADH regeneration system to provide reducing equivalents. Idramantone can be used in studies related to immunomodulation. | ||||||||||||||||||||
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Adamantane (Standard) | ≥98% | Adamantane (Standard) is the analytical standard of Adamantane. This product is intended for research and analytical applications. Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery. | ||||||||||||||||||||
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2-Adamantanol | 2-Adamantanol (Tricyclo[3.3.1.13,7]decan-2-ol) is a hydroxylated adamantane derivative formed by the removal of a secondary hydrogen atom from adamantane during ferrate-mediated hydroxylation. | |||||||||||||||||||||
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Adamantane-carboxylic acid | 99.99% | Adamantane-carboxylic acid is a compound with inhibitory activity against microorganisms. Although its specific target has not been clearly defined, it can inhibit Gram-positive bacteria and some Gram-negative bacteria. It forms a 1-monoacylglycerol derivative through a direct reaction with glycidol, and exerts its antibacterial effect by mechanisms such as altering the permeability of the bacterial cell membrane. This compound can be used in the research of antibacterial agents in the food and cosmetic industries to reduce harmful microbial flora and extend the shelf life of products. | ||||||||||||||||||||
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Adamantan-1-ylmethanamine | 99.26% | Adamantan-1-ylmethanamine (1-Aminomethyladamantane) is a Hyt hydrophobic group. Adamantan-1-ylmethanamine can be used in the synthesis of ZX782 (HY-161972). | ||||||||||||||||||||
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1-Adamantylphosphaethyne | 1-Adamantylphosphaethyne (1-(2-Phosphaethynyl)adamantane) is a compound with potential biological activity and can be used as a catalyst in organic synthesis. 1-Adamantylphosphaethyne has shown the ability to induce cell apoptosis in compound development, which helps in anti-tumor inhibition. 1-Adamantylphosphaethyne can also be used as an efficient reaction intermediate to promote the progress of various chemical reactions. | |||||||||||||||||||||
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1-Adamantanol | 99.64% | 1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials. | ||||||||||||||||||||
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