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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
1NEG
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "1NEG" in MCE Product Catalog:
Target:
Research Areas:
dTAGV-1-NEG is an inactive FKBP12 F36V PROTAC degrader, the diastereomer of dTAGV-1 (HY-145514D), and a heterobifunctional negative control molecule. dTAGV-1-NEG does not degrade any protein [1].
Cat. No.: HY-157560
Synonyms: 1NEG
Target:
Research Areas:
KDRLKZ-3 is a selective E3 ligase. KDRLKZ-3 is a ligand for KLHDC2 with a IC50 value of 4.1 μM in the alphaLISA experiment [1].
Cat. No.: HY-145514B
Target:
Research Areas:
dTAGV-1-NEG TFA is an inactive FKBP12 F36V PROTAC degrader, the diastereomer of dTAGV-1 (HY-145514D), and a heterobifunctional negative control molecule. dTAGV-1-NEG TFA does not degrade any protein [1].
Cat. No.: HY-173627
CAS No.: 1948273-05-9
Target:
Research Areas:
(R,S,S)-VH032-Me is a ligand for E3 ubiquitin ligase. (R,S,S)-VH032-Me can be connected to the ligand for protein by a linker to form dTAGV-1-NEG (HY-145514A). PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins [1].
Cat. No.: HY-173628
Research Areas:
(R,S,S)-VH032-Me-N-Boc-7-aminoheptanoic acid is a E3 Ligase Ligand-Linker Conjugate, consisting of N-Boc-7-aminoheptanoic acid (HY-W012001) and the corresponding Linker. (R,S,S)-VH032-Me-N-Boc-7-aminoheptanoic acid can be used for the synthesis of dTAGV-1-NEG (HY-145514A) [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
