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3-HBDH

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2994
    3-Hydroxybutyrate dehydrogenase

    3-HBDH

    		 Endogenous Metabolite Metabolic Disease
    3-Hydroxybutyrate dehydrogenase (3-HBDH), a mitochondrial enzyme, is a key enzyme in the ketone body metabolism pathway. 3-Hydroxybutyrate dehydrogenase is the last enzyme for ketone synthesis in the liver and the first enzyme for ketone breakdown in extracellular tissues. The absence of 3-Hydroxybutyrate dehydrogenase leads to the inhibition of fatty acid oxidation in the liver during fasting in mice, resulting in lipid accumulation and the development of fatty liver .
    3-Hydroxybutyrate dehydrogenase

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