9028-38-0
Chemical Structure
3-Hydroxybutyrate dehydrogenase
Synonym(s): 3-HBDH
- CAS No.: 9028-38-0
- Formula:N/A
- Molecular Weight:N/A
SMILES: [3-Hydroxybutyrate dehydrogenase]
Biological Activity: 3-Hydroxybutyrate dehydrogenase (3-HBDH), a mitochondrial enzyme, is a key enzyme in the ketone body metabolism pathway. 3-Hydroxybutyrate dehydrogenase is the last enzyme for ketone synthesis in the liver and the first enzyme for ketone breakdown in extracellular tissues. The absence of 3-Hydroxybutyrate dehydrogenase leads to the inhibition of fatty acid oxidation in the liver during fasting in mice, resulting in lipid accumulation and the development of fatty liver[1][2].
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3-Hydroxybutyrate dehydrogenase | 3-Hydroxybutyrate dehydrogenase (3-HBDH), a mitochondrial enzyme, is a key enzyme in the ketone body metabolism pathway. 3-Hydroxybutyrate dehydrogenase is the last enzyme for ketone synthesis in the liver and the first enzyme for ketone breakdown in extracellular tissues. The absence of 3-Hydroxybutyrate dehydrogenase leads to the inhibition of fatty acid oxidation in the liver during fasting in mice, resulting in lipid accumulation and the development of fatty liver. | |||||||||||||||||||||
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Keywords
