3 Results for "

520-33-2

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "520-33-2" in MCE Product Catalog:

30
Hesperetin
Hesperetin
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30 Cited Publications
Cat. No.: HY-N0168
CAS No.: 520-33-2
Category:  

other families Flavonoids Neurological Disease Sunscreen Flavonones Cosmetic Research Plants Disease Research Fields Cancer

Target:  

p38 MAPK Autophagy Apoptosis Reactive Oxygen Species (ROS) NF-κB Bcl-2 Family

Hesperetin is a natural flavanone that can be found in citrus, and acts as a potent and orally active broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation. Hesperetin displays a range of bioactivities including antioxidant, anti-inflammatory, and anti-cancer. Hesperetin is found to induce cell-cycle arrest at G2/M phase. Hesperetin can reduce Bcl-2 and enhance BaxM. Hesperetin induces apoptosis through inhibiting NF-κB receptor .
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Hesperetin-d3
Hesperetin-d3
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Cat. No.: HY-N0168S
Hesperetin-d3 is the deuterium labeled Hesperetin . Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis .
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(Rac)-Hesperetin-d3
(Rac)-Hesperetin-d3
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Cat. No.: HY-N0168AS
CAS No.: 1346605-26-2
(Rac)-Hesperetin-d3 is the deuterium labeled (Rac)-Hesperetin. (Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-β1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-κB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects .
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