4 Results for "

A459

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "A459" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99284
CAS No.: 1005389-60-5
Synonyms: MK-0646; h7C10

Target:  

IGF-1R Apoptosis

Research Areas:  

Cancer

Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N8207
CAS No.: 94987-10-7
Gypenoside LI, a gypenoside monomer, possesses anti-tumor activity. Gypenoside LI induces cell apoptosis, cell cycle and migration .
loading...
    loading...
Cat. No.: HY-117280
CAS No.: 1227401-27-5
Purity:  98.81%
Target:  

MDM-2/p53

Research Areas:  

Cancer

GN25 is a specific p53-Snail binding inhibitor with antitumor effects .
loading...
    loading...
Cat. No.: HY-146093
CAS No.: 2460735-29-7
Target:  

Apoptosis

Research Areas:  

Cancer

Antitumor agent-62 (Compound 47) is a NO-releasing antitumor agent. Antitumor agent-62 shows antiproliferative activity against four cancer cell lines. Antitumor agent-62 activates mitochondrial apoptosis pathway and arrests cell cycle at G2/M phase .
loading...
    loading...