2460735-29-7
Chemical Structure
Antitumor agent-62
- CAS No.: 2460735-29-7
- Formula:C21H19N3O9S
- Molecular Weight:489.46
IUPAC Name: 7-(3-((5-(l1-oxidanyl)-4-(phenylsulfonyl)-1,2,5l4-oxadiazol-3-yl)oxy)propoxy)-3-amino-6-methoxy-2H-chromen-2-one
InChIKey: FONGGCFZVFFQGL-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C=C1N)C=C(OC)C(OCCCOC3=NO[N+]([O-])=C3S(=O)(C4=CC=CC=C4)=O)=C2
Biological Activity: Antitumor agent-62 (Compound 47) is a NO-releasing antitumor agent. Antitumor agent-62 shows antiproliferative activity against four cancer cell lines. Antitumor agent-62 activates mitochondrial apoptosis pathway and arrests cell cycle at G2/M phase[1].
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Antitumor agent-62 | Antitumor agent-62 (Compound 47) is a NO-releasing antitumor agent. Antitumor agent-62 shows antiproliferative activity against four cancer cell lines. Antitumor agent-62 activates mitochondrial apoptosis pathway and arrests cell cycle at G2/M phase. | |||||||||||||||||||||
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Keywords
