1 Result for "

A769662

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "A769662" in MCE Product Catalog:

47
47 Cited Publications
Cat. No.: HY-50662
CAS No.: 844499-71-4
Target:  

AMPK

Research Areas:  

Metabolic Disease

A-769662 is a AMP-activated protein kinase (AMPK) activator. A-769662 inhibits the function of the 26S proteasome by an AMPK-independent mechanism and leads to cell cycle arrest. A-769662 directly stimulates partially purified rat liver AMPK (EC50 = 0.8 μM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC50 = 3.2 μM). A-769662 can alleviate the symptoms of metabolic diseases such as type 2 diabetes .
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