1 Result for "

ADAMTS-5-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ADAMTS-5-IN-4" in MCE Product Catalog:

Cat. No.: HY-180781
Target:  

ADAMTS

Research Areas:  

Inflammation/Immunology Cancer

ADAMTS-5-IN-4 (Compound 4b) is a selective ADAMTS5 inhibitor with an IC₅₀ of 9.4 μM. ADAMTS-5-IN-4 significantly inhibits the degradation of Aggrecan in the implants of the osteoarthritis model. ADAMTS-5-IN-4 effectively inhibits the pseudopod elongation and directional migration of ovarian cancer cells. ADAMTS-5-IN-4 shows significant cytotoxicity to HEK293T cells, human chondrocytes, and porcine chondrocyte implants. ADAMTS-5-IN-4 can be used for the study of osteoarthritis and ovarian cancer .
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