2 Results for "

AZD3759

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "AZD3759" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-18750
CAS No.: 1626387-80-1
Synonyms: AZD3759
Zorifertinib (AZD3759) is a potent, orally active, BBB-penetrant, EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.3, 0.2, and 0.2 nM for EGFR wt, EGFR L858R, and EGFR exon 19Del, respectively. Zorifertinib induces cancer cell apoptosis. Zorifertinib has antitumor activity, and can be used for NSCLC, HCC etc. research .
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Cat. No.: HY-18750A
CAS No.: 1626387-81-2
Synonyms: AZD3759 hydrochloride
Target:  

EGFR Apoptosis

Research Areas:  

Cancer

Zorifertinib (AZD3759) hydrochloride is a potent, orally active, BBB-penetrant, EGFR inhibitor (IC50s: 0.3, 0.2, and 0.2 nM for EGFR wt, EGFR L858R, and EGFR exon 19Del, respectively). Zorifertinib hydrochloride induces cancer cell apoptosis. Zorifertinib hydrochloride has antitumor activity, and can be used for NSCLC, HCC etc. research .
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