1 Result for "

AZddCTP

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AZddCTP" in MCE Product Catalog:

Cat. No.: HY-171574
CAS No.: 92562-77-1
Synonyms: AZddCTP
Target:  

HIV DNA/RNA Synthesis

Research Areas:  

Infection

3′-Azido-2′,3′-dideoxy-CTP (AZddCTP) is a cytidine analog containing a 3-azido group. As a chain terminator, 3′-Azido-2′,3′-dideoxy-CTP can be incorporated into the nascent DNA chain by HIV reverse transcriptase. 3′-Azido-2′,3′-dideoxy-CTP terminates DNA synthesis due to the lack of a 3'-hydroxyl group, thereby inhibiting viral replication. 3′-Azido-2′,3′-dideoxy-CTP has IC50 values of 15.6 μM and 160.8 μM for WT HIV and AZT R HIV. 3′-Azido-2′,3′-dideoxy-CTP has antiviral activity .
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