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3′-Azido-2′,3′-dideoxy-CTP

(Synonyms: AZddCTP)

3′-Azido-2′,3′-dideoxy-CTP (AZddCTP) is a cytidine analog containing a 3-azido group. As a chain terminator, 3′-Azido-2′,3′-dideoxy-CTP can be incorporated into the nascent DNA chain by HIV reverse transcriptase. 3′-Azido-2′,3′-dideoxy-CTP terminates DNA synthesis due to the lack of a 3'-hydroxyl group, thereby inhibiting viral replication. 3′-Azido-2′,3′-dideoxy-CTP has IC50 values of 15.6 μM and 160.8 μM for WT HIV and AZTR HIV. 3′-Azido-2′,3′-dideoxy-CTP has antiviral activity.

For research use only. We do not sell to patients.

  • CAS No.: 92562-77-1
  • Formula: C9H15N6O12P3
  • Molecular Weight:492.17
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • 3′-Azido-2′,3′-dideoxy-CTP Chemical Structure
    3′-Azido-2′,3′-dideoxy-CTP Chemical Structure
CAS No.: 92562-77-1
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All HIV Isoforms

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All DNA/RNA Synthesis Isoforms

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  • 3′-Azido-2′,3′-dideoxy-CTP Chemical Structure
    3′-Azido-2′,3′-dideoxy-CTP Chemical Structure
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  • 3′-Azido-2′,3′-dideoxy-CTP