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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Activated T Subunit
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Activated T Subunit" in MCE Product Catalog:
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Research Areas:
Activated T Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. Activated T subunit can be used for research of muscular dystrophy .
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1 Cited Publications
Cat. No.: HY-P9947
CAS No.: 214745-43-4
Synonyms: Ro 24-7375
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Cat. No.: HY-P991424
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U93631 is a GABAA receptor inhibitor targeting the picrotoxin (HY-101391) site, which exhibits higher inhibitory potency in receptors lacking α subunits. U93631 blocks GABA-induced chloride currents, exerts a mild initial stimulatory effect on activated currents, but its activity decreases in β2T246F mutant receptors. U93631 can serve as a ligand for the convulsant site of GABAA receptors in relevant studies .
Cat. No.: HY-153406A
CAS No.: 1155373-34-4
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(rac)-Activated T subunit is the racemate of Activated T Subunit (HY-153406). Activated T Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. (rac)-Activated T subunit can be used for research of muscular dystrophy .
Cat. No.: HY-P705862
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PRKACA; CDNA FLJ58698, Highly Similar To CAMP-Dependent Protein Kinase, Alpha-Catalytic Subunit; Protein Kinase CAMP-Activated Catalytic Subunit Alpha; Protein Kinase A Catalytic Subunit; CAMP-Dependent Protein Kinase Catalytic Subunit Alpha; Protein Kina
Cat. No.: HY-179499
CAS No.: 2978620-84-5
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PROTAC EZH2 Degrader-9 is orally active EZH2 PROTAC degrader degrading EZH2 via the ubiquitin-proteasome pathway. PROTAC EZH2 Degrader-9 downregulates PRC2 core subunits and potent inhibition of H3K27me3 without affecting common CRBN neosubstrates while it was selective over GSp'T1 and ikZF1/3. PROTAC EZH2 Degrader-9 exhibits potent antiproliferative activity against multiple cancer cell lines by inducing cell cycle and apoptosis. PROTAC EZH2 Degrader-9 reverses PRC2-mediated gene silencing and inhibiting EZH2 non-catalytic target gene activation. PROTAC EZH2 Degrader-9 can be used for leukemia, lymphoma, and non-small cell lung cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
