1 Result for "

AktS473

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "AktS473" in MCE Product Catalog:

  • Targets Recommended:
Artocarpin
Artocarpin
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Cat. No.: HY-N2902
CAS No.: 7608-44-8
Category:  

Flavonols Flavonoids Plants Moraceae

Target:  

Reactive Oxygen Species (ROS)

Artocarpin is an orally active apoptosis inducer. Artocarpin targets NF-κB, Erk1/2, p38 MAPK, AktS473, p53, Akt 1 kinase and Akt 2 kinase. Artocarpin induces reactive oxygen species (ROS) production, mediates p53-dependent and p53-independent apoptotic signaling pathways, induces G1-phase cell cycle arrest, and triggers autophagic cell death. Artocarpin exerts cytotoxic and bactericidal effects on cancer cells, reduces bacterial load, and exhibits anti-inflammatory, analgesic and anti-angiogenic activities .
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