8 Results for "

Alloc-Val-Ala-pAB

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Alloc-Val-Ala-pAB" in MCE Product Catalog:

Cat. No.: HY-W071967
CAS No.: 1343407-91-9
Target:  

ADC Linkers

Research Areas:  

Cancer

Alloc-Val-Ala-PAB is a peptide cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Ala will specifically be cleaved by Cathepsin B. The Alloc group is stable to treatment with piperidine and TFA, but can be easily removed under mild conditions by palladium catalyzed allyl transfer.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-13545
CAS No.: 251579-55-2
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

ABT-510 is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer. ABT-510 also reduces angiogenesis and inflammatory responses in a murine model of inflammatory bowel disease. ABT-510 can be used in studies of cancer (particularly epithelial ovarian cancer) and inflammatory bowel disease (IBD) .
loading...
    loading...
Cat. No.: HY-W591336
CAS No.: 1884578-27-1
Target:  

ADC Linkers

Research Areas:  

Cancer

Alloc-Val-Ala-PAB-PNP is a cleavable ADC linker.
loading...
    loading...
Cat. No.: HY-W101299
CAS No.: 54831-20-8
Research Areas:  

Metabolic Disease

N-Acetyl-D-allo-isoleucine is an amino acid derivative. N-Acetyl-D-allo-isoleucine is promising for research of amino acid metabolism, such as abnormal isoleucine metabolism .
loading...
    loading...
Cat. No.: HY-P4910
CAS No.: 1622872-91-6
Target:  

Proteasome Apoptosis

Research Areas:  

Cancer

Baceridin is a proteasome inhibitor and a cyclic hexapeptide. Baceridin can be isolated from the culture medium of Epiphytic Bacillus. Baceridin can inhibit cell cycle progression and induce tumor cell apoptosis through a p53-independent pathway. Baceridin can be used in cancer research .
loading...
    loading...
Cat. No.: HY-P2120
CAS No.: 79438-64-5
Target:  

Bacterial

Research Areas:  

Others

Pseudobactin A is a non-fluorescent extracellular iron carrier produced by the plant growth-promoting bacterium Pseudomonas B10 .
loading...
    loading...
Cat. No.: HY-P4613
CAS No.: 130674-54-3
Research Areas:  

Others

Fmoc-D-allo-Thr-OH is a derivative of D-allothreonine (HY-W001959), which is commonly used as a building block in solid-phase peptide synthesis (SPPS) .
loading...
    loading...
Cat. No.: HY-P11022
CAS No.: 55599-68-3
Synonyms: A-3302-B
Research Areas:  

Infection Cancer

TL-119 (A-3302-B) is a polypeptide. TL-119 can be isolated from the bacteria Micromonospora sp. MAG 9-7 and Saccharomonospora sp. CNQ-490. TL-119 inhibits TRPV-1. TL-119 exhibits antiviral activity against HSV-2. TL-119 possesses anticancer activity against gastric cancer and colorectal cancer .
loading...
    loading...