55599-68-3
55599-68-3
Chemical Structure
TL-119
Synonym(s): A-3302-B
- CAS No.: 55599-68-3
- Formula:C36H46N6O8
- Molecular Weight:690.79
InChIKey: NUKXVWPUFGMEDK-MXUYVNIMSA-N
SMILES: O=C(N[C@H](C(N[C@H](C(N/C(C(O[C@@H]1C)=O)=C\C)=O)C)=O)C(C)C)[C@@H]1NC([C@@H](NC([C@H](NC(C)=O)CC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O
Biological Activity: TL-119 (A-3302-B) is a polypeptide. TL-119 can be isolated from the bacteria Micromonospora sp. MAG 9-7 and Saccharomonospora sp. CNQ-490. TL-119 inhibits TRPV-1. TL-119 exhibits antiviral activity against HSV-2. TL-119 possesses anticancer activity against gastric cancer and colorectal cancer[1][2].
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TL-119 | TL-119 (A-3302-B) is a polypeptide. TL-119 can be isolated from the bacteria Micromonospora sp. MAG 9-7 and Saccharomonospora sp. CNQ-490. TL-119 inhibits TRPV-1. TL-119 exhibits antiviral activity against HSV-2. TL-119 possesses anticancer activity against gastric cancer and colorectal cancer. | |||||||||||||||||||||
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References
- [1]. Sureram S, et al. The Peptide A-3302-B Isolated from a Marine Bacterium Micromonospora sp. Inhibits HSV-2 Infection by Preventing the Viral Egress from Host Cells. Int J Mol Sci. 2022 Jan 15;23(2):947. [Content Brief]
- [2]. Le TC, et al. Marine Depsipeptide Nobilamide I Inhibits Cancer Cell Motility and Tumorigenicity via Suppressing Epithelial-Mesenchymal Transition and MMP2/9 Expression. ACS Omega. 2022;7(2):1722-1732. Published 2022 Jan 3. [Content Brief]
