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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Arotinoid
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Arotinoid" in MCE Product Catalog:
Synonyms: Ro 13-6298; Arotinoid ethyl ester
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Arotinoid (RO 13-6298) is a retinoid, and acts as an orally active and highly potent agonist of retinoic acid receptors (RARs) with antipsoriatic effects. Arotinoid has antipapiltoma activity with an ED50 of 0.05 mg/kg. Arotinoid can be used for the research of skin carcinomas .
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6 Cited Publications
Synonyms: Ro 13-7410; Arotinoid acid; AGN191183
TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively.
Cat. No.: HY-15682G
CAS No.: 71441-28-6
Synonyms: Ro 13-7410 (GMP); Arotinoid acid (GMP); AGN191183 (GMP)
Cat. No.: HY-127149
CAS No.: 125533-88-2
Synonyms: Ro 40-8757
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Mofarotene (Ro 40-8757), an arotinoid, is anticancer compound. Mofarotene induces apoptosis, associated with mitochondrial membrane depolarization, activation of caspase-3 and -9, and enhanced production of reactive oxygen species. Mofarotene inhibits hematopoiesis in vitro by inhibiting maturation from primitive progenitor cells .
Cat. No.: HY-113840
CAS No.: 105687-93-2
Synonyms: Ro 14-9706
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Sumarotene (Ro 14-9706), an arotinoid methyl sulfone, is a potent dermatologic agent for the repair of photodamage, antikeratinization, and antiproliferation. Sumarotene exhibits in rats a prolactin-suppressive activity which affects lactation .
Cat. No.: HY-U00011
CAS No.: 75078-91-0
Synonyms: Ro 15-0778
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Temarotene is an orally administered, particular arotinoid .
Cat. No.: HY-106735R
CAS No.: 71441-09-3
Synonyms: Ro 13-6298 (Standard); Arotinoid ethyl ester (Standard)
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Arotinoid (Standard) (Ro 13-6298 (Standard)) is the analytical standard of Arotinoid (HY-106735). This product is intended for research and analytical applications. Arotinoid (RO 13-6298) is a retinoid, and acts as an orally active and highly potent agonist of retinoic acid receptors (RARs) with antipsoriatic effects. Arotinoid has antipapiltoma activity with an ED50 of 0.05 mg/kg. Arotinoid can be used for the research of sKin carcinomas .
Cat. No.: HY-15682R
CAS No.: 71441-28-6
Synonyms: Ro 13-7410 (Standard); Arotinoid acid (Standard); AGN191183 (Standard)
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Research Areas:
TTNPB (Standard) is the analytical standard of TTNPB. This product is intended for research and analytical applications. TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively.
Cat. No.: HY-19590
CAS No.: 87719-32-2
Synonyms: Ro 15-1570
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Etarotene (Ro 15-1570) is a derivative of Arotinoid (HY-106735). Etarotene is an orally active antitumor agent against DMBA (HY-W011845)-induced mammary tumor and causes toxic symptoms of hypervitaminosis A in rat model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
