Search Result

Results for "

Atractylodes macrocephala

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Apoptosis (1) Histone Demethylase (1) JAK (2) NO Synthase (1) Reference Standards (1) STAT (2) TNF Receptor (2) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (3) Inflammation/Immunology (2) Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0201

Atractylenolide I 5 Publications Verification	TNF Receptor Toll-like Receptor (TLR) JAK STAT	Cancer
Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.

HY-N10131

Biatractylolide (+)-Biatractylolide	Apoptosis	Neurological Disease Cancer
Biatractylolide is a compound isolated from the ethyl acetate extract of Atractylodes macrocephala. Biatractylolide has antitumor and antioxidant activities. Biatractylolide improves cell viability, inhibits the apoptosis of cells induced by glutamate, and reduces the activity of LDH. Biatractylolide has neuroprotective effects .

HY-N8830

Selina-4(14),7(11)-dien-8-one	Others	Others
Selina-4(14),7(11)-dien-8-one is a sesquiterpene that can be isolated from Atractylodes Macrocephala Rhizoma .

HY-176254

LSD1-IN-43	Histone Demethylase Amyloid-β	Neurological Disease
LSD1-IN-43 is a highly selective, reversible, orally active and brain-penetrant LSD1 inhibitor with an IC₅₀ value of 0.8 μM. LSD1-IN-43 has low inhibitory activity against MAO-A and MAO-B, two homologs of LSD1. LSD1-IN-43 significantly inhibits Aβ aggregation and enhances Aβ-induced neuronal cell viability. LSD1-IN-43 can be used for the study of Alzheimer’s disease (AD).

HY-N0201R

Atractylenolide I (Standard)	TNF Receptor Reference Standards Toll-like Receptor (TLR) JAK STAT	Cancer
Atractylenolide I (Standard) is the analytical standard of Atractylenolide I. This product is intended for research and analytical applications. Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.

HY-N9201

8beta-Methoxyatractylenolide I	Others	Others
8beta-Methoxyatractylenolide I is a Sesquiterpenoids product that can be isolated from the rhizomes of Atractylodes macrocephala. .

HY-N18146

14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol	Others	Inflammation/Immunology
14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol is an orally active acetylenic compound present in the rhizomes of Atractylodes macrocephala Koidz. 14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol is applicable to the research of acute inflammation .

HY-N17540

8-Epiasterolide	NO Synthase	Inflammation/Immunology
8-Epiasterolide is a sesquiterpenoid compound isolated from the rhizomes of Atractylodes japonica Koidzumi. 8-Epiasterolide inhibits NO production in LPS (HY-D1056)-treated RAW 264.7 cells. 8-Epiasterolide can be used in the study of inflammatory diseases .

Atractylenolide I 5 Publications Verification	Classification of Application Fields Terpenoids Sesquiterpenes Astragalus caprinus L. Plants Compositae Disease Research Fields Source Classification Cancer	TNF Receptor Toll-like Receptor (TLR) JAK STAT
Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.

Selina-4(14),7(11)-dien-8-one	Terpenoids Sesquiterpenes Astragalus caprinus L. Plants Compositae Source Classification	Others
Selina-4(14),7(11)-dien-8-one is a sesquiterpene that can be isolated from Atractylodes Macrocephala Rhizoma .

Atractylenolide I (Standard)	Structural Classification Terpenoids Sesquiterpenes Astragalus caprinus L. Plants Compositae Source Classification	TNF Receptor Reference Standards Toll-like Receptor (TLR) JAK STAT
Atractylenolide I (Standard) is the analytical standard of Atractylenolide I. This product is intended for research and analytical applications. Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.

8beta-Methoxyatractylenolide I	Terpenoids Sesquiterpenes Astragalus caprinus L. Plants Compositae Source Classification	Others
8beta-Methoxyatractylenolide I is a Sesquiterpenoids product that can be isolated from the rhizomes of Atractylodes macrocephala. .

14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol	Structural Classification Natural Products Astragalus caprinus L. Plants Compositae Source Classification	Others
14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol is an orally active acetylenic compound present in the rhizomes of Atractylodes macrocephala Koidz. 14-Acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol is applicable to the research of acute inflammation .

8-Epiasterolide	Structural Classification Terpenoids Sesquiterpenes Plants Compositae Source Classification Erythrina sigmoidea Hua	NO Synthase
8-Epiasterolide is a sesquiterpenoid compound isolated from the rhizomes of Atractylodes japonica Koidzumi. 8-Epiasterolide inhibits NO production in LPS (HY-D1056)-treated RAW 264.7 cells. 8-Epiasterolide can be used in the study of inflammatory diseases .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Name
Email *

	Sorry, but the email address you supplied was invalid.

Atractylodes macrocephala

Inhibitors & Agonists

NaturalProducts

Natural
Products