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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Azaindole
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Azaindole" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: ROCK-IN-2; Azaindole 1; TC-S 7001
Target:
Research Areas:
BAY-549 (Azaindole 1), a chemical probe, is an orally active and ATP-competitive ROCK inhibitor with IC50s of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2, respectively .
1
1 Cited Publications
Cat. No.: HY-30014
CAS No.: 348640-06-2
Cat. No.: HY-30012
CAS No.: 183208-35-7
Cat. No.: HY-50471
CAS No.: 183208-36-8
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Research Areas:
5-Methoxy-7-azaindole is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-30013
CAS No.: 55052-28-3
Cat. No.: HY-30156
CAS No.: 10592-27-5
Synonyms: 7-Azaindoline
Cat. No.: HY-20553
CAS No.: 951625-93-7
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Methyl 4-chloro-7-azaindole-5-carboxylate is a drug intermediate for synthesis of various active compounds.
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MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-30011
CAS No.: 866546-07-8
Synonyms: 5-chloro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-1H-pyrrolo[2,3-b]pyridine
Cat. No.: HY-W002711
CAS No.: 271-34-1
Cat. No.: HY-30017
CAS No.: 74420-15-8
Cat. No.: HY-176065
CAS No.: 3084825-09-9
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Research Areas:
Nav1.2-IN-1 (compound 5i), a 3-(1,2,3,6-tetrahydropyridine)-4-azaindole derivative, is a potent and selective Nav1.2 inhibitor. Nav1.2-IN-1 induces a reduction in the peak amplitude of Nav1.2 currents with an IC50 value of 7.79 μM. Nav1.2-IN-1 exhibits antiepileptic activity. Nav1.2-IN-1 shows high anticonvulsant effect and low neurotoxicity in subcutaneous Pentetrazole (sc-PTZ)-induced epilepsy mode .
Cat. No.: HY-W090805
CAS No.: 1190319-16-4
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5-Bromo-3-iodo-4-azaindole is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-10319R
CAS No.: 867017-68-3
Synonyms: ROCK-IN-2 (Standard); Azaindole 1 (Standard); TC-S 7001 (Standard)
Target:
Research Areas:
BAY-549 (Standard) is the analytical standard of BAY-549 (HY-10319). This product is intended for research and analytical applications. BAY-549 (Azaindole 1), a chemical probe, is an orally active and ATP-competitive ROCK inhibitor with IC50s of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2, respectively .
Cat. No.: HY-W001520
CAS No.: 27257-15-4
Target:
1-Methyl-1H-pyrrolopyridine is a 7-azaindole derivative that binds to the EGFR kinase domain. It inhibits the growth of breast cancer cells but shows no activity against lung cancer and liver cancer cells. 1-Methyl-1H-pyrrolopyridine can be used in breast cancer research .
Cat. No.: HY-183005
CAS No.: 3039974-31-4
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Research Areas:
ActRIIB-IN-1, 7-azaindole compound is an orally active activin type II receptor B (ActRIIB) inhibitor with an IC50 of 1.8 nM. ActRIIB-IN-1 can alleviate weight loss, muscle atrophy and decreased muscle strength caused by tumor cachexia, as well as improve appetite. ActRIIB-IN-1 can be used for the research of cancer cachexia .
Cat. No.: HY-P4948
CAS No.: 1926163-49-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
