2,3-Dihydro-7-azaindole
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2,3-Dihydro-7-azaindole (7-Azaindoline) is a cyclic secondary amine substrate with a fused aromatic ring, which serves as a substrate for hydrogenation reactions. 2,3-Dihydro-7-azaindole undergoes amidation with methyl pyrazine-2-carboxylate under the catalysis of lipase from Pseudomonas stutzeri. 2,3-Dihydro-7-azaindole is often used as an intermediate in organic synthesis, for example, in the preparation of indole compounds.
For research use only. We do not sell to patients.
- Purity : 99.96%
- CAS No.: 10592-27-5
- Formula: C7H8N2
- Molecular Weight:120.16
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
2,3‑Dihydro‑7‑azaindole undergoes selective hydrogenation on its heteroaromatic ring to afford a partially saturated heterocycle; furthermore, a saturated N‑heterocyclic product can be obtained in the partial hydrogenation reaction catalyzed by the RuO2@PNC nanocatalyst.[1].
2,3-Dihydro-7-azaindole undergoes amidation with methyl pyrazine-2-carboxylate under the catalysis of Pseudomonas stutzeri lipase[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 10592-27-5
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Appearance Solid
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Molecular Weight 120.16
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Formula C7H8N2
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Color White to off-white
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SMILES
C12=CC=CN=C1NCC2
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Synonyms
7-Azaindoline
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (832.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (290 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.3222 mL | 41.6112 mL | 83.2224 mL | 208.0559 mL |
| 5 mM | 1.6644 mL | 8.3222 mL | 16.6445 mL | 41.6112 mL | |
| 10 mM | 0.8322 mL | 4.1611 mL | 8.3222 mL | 20.8056 mL | |
| 15 mM | 0.5548 mL | 2.7741 mL | 5.5482 mL | 13.8704 mL | |
| 20 mM | 0.4161 mL | 2.0806 mL | 4.1611 mL | 10.4028 mL | |
| 25 mM | 0.3329 mL | 1.6644 mL | 3.3289 mL | 8.3222 mL | |
| 30 mM | 0.2774 mL | 1.3870 mL | 2.7741 mL | 6.9352 mL | |
| 40 mM | 0.2081 mL | 1.0403 mL | 2.0806 mL | 5.2014 mL | |
| 50 mM | 0.1664 mL | 0.8322 mL | 1.6644 mL | 4.1611 mL | |
| 60 mM | 0.1387 mL | 0.6935 mL | 1.3870 mL | 3.4676 mL | |
| 80 mM | 0.1040 mL | 0.5201 mL | 1.0403 mL | 2.6007 mL | |
| 100 mM | 0.0832 mL | 0.4161 mL | 0.8322 mL | 2.0806 mL |
2,3-Dihydro-7-azaindole Related Classifications
HY-30156 Related Classifications
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