3039974-31-4
3039974-31-4
Chemical Structure
ActRIIB-IN-1
- CAS No.: 3039974-31-4
- Formula:C21H22N6
- Molecular Weight:358.45
IUPAC Name: 5-(4-(4-methylpiperazin-1-yl)phenyl)-3-(1H-pyrazol-3-yl)-1H-pyrrolo[2,3-b]pyridine
InChIKey: ZGPUJEKEYUKANO-UHFFFAOYSA-N
SMILES: N=1C=C(C=C2C1NC=C2C3=NNC=C3)C=4C=CC(=CC4)N5CCN(C)CC5
Biological Activity: ActRIIB-IN-1, 7-azaindole compound is an orally active activin type II receptor B (ActRIIB) inhibitor with an IC50 of 1.8 nM. ActRIIB-IN-1 can alleviate weight loss, muscle atrophy and decreased muscle strength caused by tumor cachexia, as well as improve appetite. ActRIIB-IN-1 can be used for the research of cancer cachexia[1].
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ActRIIB-IN-1 | ActRIIB-IN-1, 7-azaindole compound is an orally active activin type II receptor B (ActRIIB) inhibitor with an IC50 of 1.8 nM. ActRIIB-IN-1 can alleviate weight loss, muscle atrophy and decreased muscle strength caused by tumor cachexia, as well as improve appetite. ActRIIB-IN-1 can be used for the research of cancer cachexia. | |||||||||||||||||||||
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