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Nav1.2-IN-1

Nav1.2-IN-1 (compound 5i), a 3-(1,2,3,6-tetrahydropyridine)-4-azaindole derivative, is a potent and selective Nav1.2 inhibitor. Nav1.2-IN-1 induces a reduction in the peak amplitude of Nav1.2 currents with an IC50 value of 7.79 μM. Nav1.2-IN-1 exhibits antiepileptic activity. Nav1.2-IN-1 shows high anticonvulsant effect and low neurotoxicity in subcutaneous Pentetrazole (sc-PTZ)-induced epilepsy mode.

For research use only. We do not sell to patients.

  • CAS No.: 3084825-09-9
  • Formula: C20H18F3N3
  • Molecular Weight:357.37
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Nav1.2-IN-1 Chemical Structure
    Nav1.2-IN-1 Chemical Structure
CAS No.: 3084825-09-9
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  • Nav1.2-IN-1 Chemical Structure
    Nav1.2-IN-1 Chemical Structure
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  • Nav1.2-IN-1