2 Results for "

BA-3011

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "BA-3011" in MCE Product Catalog:

Cat. No.: HY-145622
CAS No.: 2460400-64-8
Synonyms: BA3011; CAB-Axl-ADC; CAB-anti-Axl-ADC
Mecbotamab vedotin (BA3011) is a pH dependent antibody drug conjugate (ADC) targeting AXL. Mecbotamab vedotin can significantly inhibit AXL in DU145 cells and LCLC-103H cells and kills cells. Mecbotamab vedotin can be used for research on cancer such as lung cancer, pancreatic cancer and prostate cancer. The antibody component is Mecbotamab (HY-P9988), and the ADC toxin molecule is Monomethyl auristatin E (MMAE) (HY-15162) .
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Cat. No.: HY-P9988
CAS No.: 2460400-28-4
Synonyms: BA301

Research Areas:  

Cancer

Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011) .
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