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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
BCPyr
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "BCPyr" in MCE Product Catalog:
Cat. No.: HY-142621
CAS No.: 2669844-82-8
BCPyr is a PROTAC degrader targeting cIAP1 and BTK, with a Kd of 262 nM for human cIAP1, and Kd values of 262 nM and 692 nM for human BTK. BCPyr binds to the Bir3 domain of cIAP1, recruits BTK to cIAP1, and mediates the ubiquitination and degradation of BTK. BCPyr acts as a degrader, ternary complex stabilizer, cooperative binder, and higher-order assembly inducer. BCPyr can be used in studies related to leukemia and lymphoma .
Cat. No.: HY-168315
Target:
Research Areas:
(5-(Bromomethyl)pyrazin-2-yl)methanol is a linker, that can be used for synthesis of PROTAC degrader BCPyr (HY-142621) .
Cat. No.: HY-168314
Research Areas:
BTK ligand 11 is a PROTAC target protein ligand that can be used to synthesize BCPyr (HY-142621) .
Cat. No.: HY-168316
Research Areas:
E3 Ligase Ligand-linker Conjugate 146 is a PROTAC E3 ubiquitin ligase ligand and linker, used for synthesizing BCPyr (HY-142621) .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
