1 Result for "

BI186908

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BI186908" in MCE Product Catalog:

Cat. No.: HY-120847
CAS No.: 1453500-36-1
Target:  

MCHR1 (GPR24)

BI 186908 is a selective and orally active MCH receptor 1 antagonist with an IC50 of 22 nM and a Ki of 14 nM. BI 186908 binds with comparably high affinity to the recombinant human, cynomolgus monkey (IC50 of 18 nM), dog (IC50 of 23 nM) and rat (IC50 of 18 nM) MCH-R1. BI 186908 can significantly reduce the body weight of diet-induced obese rats. BI 186908 can be used for the study of obesity .
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