1 Result for "

BMS-869780

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BMS-869780" in MCE Product Catalog:

Cat. No.: HY-18326
CAS No.: 1235493-78-3
Target:  

γ-secretase Amyloid-β

Research Areas:  

Neurological Disease

BMS-869780 is an orally active non-acidic γ-secretase (γ-secretase) modulator. BMS-869780 regulates the activity of γ-secretase, thereby altering the production profile of β-amyloid proteins. When acting alone, it changes the relative levels of specific β-amyloid subtypes without inhibiting the total production of β-amyloid proteins. BMS-869780 exerts a synergistic effect with γ-secretase modulators of the acidic structural class to inhibit the total production of β-amyloid proteins in cell cultures .
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