5 Results for "

BRO

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "BRO" in MCE Product Catalog:

39
39 Cited Publications
Cat. No.: HY-12137
CAS No.: 755038-65-4
Purity:  99.87%
Synonyms: BI 6727
Research Areas:  

Cancer

Volasertib (BI 6727) is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. Volasertib inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib induces mitotic arrest and apoptosis. Volasertib, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models .
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39
39 Cited Publications
Cat. No.: HY-12137A
CAS No.: 946161-17-7
Synonyms: BI 6727 trihydrochloride
Research Areas:  

Cancer

Volasertib (BI 6727) trihydrochloride is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. Volasertib trihydrochloride inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib trihydrochloride induces mitotic arrest and apoptosis. Volasertib trihydrochloride, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models .
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Cat. No.: HY-77910
CAS No.: 57988-58-6
Synonyms: BPHP
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

4-(4-Bromophenyl)-4-hydroxypiperidine (BPHP) is a metabolite of Bromperidol (BRO) (HY-B0901) and is produced by N-dealkylation of BRO .
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Cat. No.: HY-12137R
CAS No.: 755038-65-4
Synonyms: BI 6727 (Standard)
Volasertib (Standard) is the analytical standard of Volasertib. This product is intended for research and analytical applications. Volasertib (BI 6727) is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. Volasertib inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib induces mitotic arrest and apoptosis. Volasertib, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models .
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Cat. No.: HY-105560
CAS No.: 41952-52-7
Research Areas:  

Infection

Cefcanel is an orally active cephalosporin and antibacterial agent. Cefcanel inhibits growth of methicillin-susceptible Staphylococcus aureus, methicillin-susceptible Staphylococcus epidermidis, Haemophilus influenzae, Moraxella catarrhalis. Cefcanel acts as a substrate hydrolyzed by TEM-1, TEM-3, and Moraxella Bro-1 beta-lactamases .
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