Cefcanel
Cefcanel is an orally active cephalosporin and antibacterial agent. Cefcanel inhibits growth of methicillin-susceptible Staphylococcus aureus, methicillin-susceptible Staphylococcus epidermidis, Haemophilus influenzae, Moraxella catarrhalis. Cefcanel acts as a substrate hydrolyzed by TEM-1, TEM-3, and Moraxella Bro-1 beta-lactamases.
For research use only. We do not sell to patients.
- CAS No.: 41952-52-7
- Formula: C19H18N4O5S3
- Molecular Weight:478.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Beta-lactamase Isoforms
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Biological Activity
Cefcanel (18-20 h) exhibits potent in vitro activity against a variety of aerobic Gram-positive bacteria, including methicillin-sensitive *Staphylococcus aureus* (MIC90 1 μg/mL) and methicillin-sensitive *Staphylococcus epidermidis* (MIC90 1 μg/mL)[1].
Cefcanel (18-20 h) exhibits variable in vitro activity against aerobic Gram-negative bacteria. It shows potent activity against *Klebsiella pneumoniae* (MIC90 2 μg/mL), *Citrobacter diversus* (MIC90 2 μg/mL), *Aeromonas hydrophila* (MIC90 1 μg/mL), *Haemophilus influenzae* (MIC90 1 μg/mL) and *Moraxella catarrhalis* (MIC90 1 μg/mL), but is inactive against *Serratia marcescens*, *Pseudomonas aeruginosa* and *Acinetobacter calcoaceticus*[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 41952-52-7
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Molecular Weight 478.57
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Formula C19H18N4O5S3
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SMILES
OC(C1=C(CSC2=NN=C(C)S2)CS[C@@]([C@@H]3NC([C@@H](C4=CC=CC=C4)O)=O)([H])N1C3=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Cefcanel
- 41952-52-7
- Bacterial
- Beta-lactamase
- Escherichia coli
- methicillin-susceptible Staphylococcus aureus
- Haemophilus influenzae
- Clostridium perfringens
- Streptococcus pyogenes
- Moraxella catarrhalis
- Streptococcus pneumoniae
- beta-lactamases
- methicillin-susceptible Staphylococcus epidermidis
- Klebsiella pneumoniae
- Inhibitor
- inhibitor
- inhibit