1 Result for "

BV 1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "BV 1" in MCE Product Catalog:

BV-1
BV-1
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Cat. No.: HY-D3108
CAS No.: 2569032-08-0
BV-1 is a fluorescent probe for detecting mitochondrial viscosity in living cells. The detection mechanism of BV-1 relies on a twisted intramolecular charge transfer (TICT) mechanism associated with environmental viscosity: in low-viscosity media, the unsaturated domain at the meso-position of the BODIPY fluorophore undergoes TICT, achieving efficient excited-state deactivation through molecular rotation, thereby quenching fluorescence; under high-viscosity conditions, such molecular rotation is restricted, TICT is inhibited, and the conjugated system of the probe extends, which leads to significant fluorescence enhancement accompanied by a red shift in emission wavelength. BV-1 exhibits low cytotoxicity. Its detection wavelengths include excitation wavelengths of 480 nm or 488 nm, with an emission wavelength of 545 nm in low-viscosity environments and 570 nm in high-viscosity environments; in addition, its absorption peak locates at 528 nm in ethanol and red-shifts to 531 nm in glycerol .
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