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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
Blimp1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "Blimp1" in MCE Product Catalog:
Cat. No.: HY-180178
Research Areas:
BLIMP-1 ligand-1 (Compound 56) is a BLIMP-1 ligand. BLIMP-1 ligand-1 can be used as a ligand for target protein for PROTAC to develop and design degraders of PROTAC BLIMP-1, such as PROTAC BLIMP-1 degrader-1 (HY-180177). BLIMP-1 ligand-1 can be used in multiple myeloma research [1].
Cat. No.: HY-180177
Target:
Research Areas:
PROTAC BLIMP-1 degrader-1 is an orally active BLIMP-1 PROTAC degrader with an EC50 of 13.1 nM. PROTAC BLIMP-1 degrader-1 recruits the neprilysin (CRBN) E3 ligase to mediate ubiquitination and subsequent degradation of BLIMP-1α via the 26S proteasome, without affecting the BLIMP-1β isoform. PROTAC BLIMP-1 degrader-1 inhibits cancer cell proliferation and tumor growth. It can be used in research related to multiple myeloma [1].
Cat. No.: HY-180179
Research Areas:
BLIMP-1 Ligand-Linker Conjugate 1 is a conjugate of BLIMP-1 Ligand-1 (HY-180178) and Linker (HY-180180). BLIMP-1 ligand-Linker Conjugate 1 can be coupled with CRBN ligand-881 (HY-W442918) to form PROTAC BLIMP-1 degrader-1 (HY-180177) [1].
Cat. No.: HY-RS11059
Target:
Research Areas:
PRDM1 Human Pre-designed siRNA Set A contains three designed siRNAs for PRDM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19474
Target:
Research Areas:
Prdm1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Prdm1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-180180
Target:
Research Areas:
trans-5-(4-(Hydroxymethyl)cyclohexyl)-6-methylpicolinic acid is a PROTAC linker. trans-5-(4-(Hydroxymethyl)cyclohexyl)-6-methylpicolinic acid can be used to synthesize PROTAC BLIMP-1 degrader-1 (HY-180177) [1].
Cat. No.: HY-P85055
Synonyms: PRDM1; Blimp1; PR domain zinc finger protein 1; Blimp-1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1; Positive regulatory domain I-binding factor 1; PRDI-BF1; PRDI-binding factor 1
Cat. No.: HY-P81356
Synonyms: PRDM1; Blimp1; PR domain zinc finger protein 1; Blimp-1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1; Positive regulatory domain I-binding factor 1 (PRDI-BF1; PRDI-binding factor 1)
Cat. No.: HY-P81356A
Synonyms: PRDM1; Blimp1; PR domain zinc finger protein 1; Blimp-1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1; Positive regulatory domain I-binding factor 1 (PRDI-BF1; PRDI-binding factor 1)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
