2. PROTAC
  3. PROTACs
  4. PROTAC BLIMP-1 degrader-1

PROTAC BLIMP-1 degrader-1 (Compound 49) is a PROTAC-based BLIMP-1 degrader. PROTAC BLIMP-1 degrader-1 promotes the ubiquitination and degradation of BLIMP-1 and can be used in research on myeloproliferative tumors.
(Pink: Ligands for Target Protein for PROTAC ligand (HY-180178); Blue: Ligands for E3 Ligase and Cereblon ligand (HY-W442918); Black: linker (HY-180180)).

For research use only. We do not sell to patients.

PROTAC BLIMP-1 degrader-1

PROTAC BLIMP-1 degrader-1 Chemical Structure

Size Price Stock
1 mg Ask For Quote & Lead Time
5 mg Ask For Quote & Lead Time

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

PROTAC BLIMP-1 degrader-1 Related Antibodies

Top Publications Citing Use of Products

View All PROTACs Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

PROTAC BLIMP-1 degrader-1 (Compound 49) is a PROTAC-based BLIMP-1 degrader. PROTAC BLIMP-1 degrader-1 promotes the ubiquitination and degradation of BLIMP-1 and can be used in research on myeloproliferative tumors[1]. (Pink: Ligands for Target Protein for PROTAC ligand (HY-180178); Blue: Ligands for E3 Ligase and Cereblon ligand (HY-W442918); Black: linker (HY-180180)).

Molecular Weight

795.77

Formula

C41H47BrN8O4
SMILES

CC1=CC(Br)=CC=C1[C@@H](C(N)=O)N2CCN3N=C(C=C3C2)CNC(C4=NC(C)=C([C@H]5CC[C@@H](CC5)CNC6=CC=C(C7CCC(NC7=O)=O)C=C6)C=C4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

PROTAC BLIMP-1 degrader-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC BLIMP-1 degrader-1PROTACsMultiple myelomaMM1.sOPM2Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PROTAC BLIMP-1 degrader-1
Cat. No.:
HY-180177
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.