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Results for "

C-5 position

" in MedChemExpress (MCE) Product Catalog:

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Biochemical Assay Reagents

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Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W008137
    5-Bromo-2-fluoropyrimidine

    		Biochemical Assay Reagents Others
    5-Bromo-2-fluoropyrimidine is a polyhalogenated pyrimidine and chemoselective amination substrate.5-Bromo-2-fluoropyrimidine undergoes chemoselective amination at the C-2 position (C-F bond) with no amination at the C-5 position (C-Br bond) in the presence of a Cu(II)/PTABS catalytic system .
    5-Bromo-2-fluoropyrimidine
  • HY-E70206
    CpG Methyltransferase

    CpG

    		 DNA Methyltransferase Biochemical Assay Reagents Others Cancer
    CpG Methyltransferase is a DNA methyltransferase. CpG Methyltransferase can methylate the C5 position on the base moiety of all cytosine nucleotides contained in unmethylated or hemimethylated double stranded DNA in a 5’-CpG-3’ context .
    CpG Methyltransferase
  • HY-N13081
    3-Oxo-cinobufagin

    		Others Cancer
    3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagin's cytotoxicity against cancer cells are: 71.3 μM (HepG2), 90.2 μM (SMMC-7221), 0.11 μM (BEL-7402), 72.5 μM (K562), 5.3 μM (HL-60), and 12 nM (HEL) .
    3-Oxo-cinobufagin

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