5-Bromo-2-fluoropyrimidine
Based on 1 Customer Validation
5-Bromo-2-fluoropyrimidine is a polyhalogenated pyrimidine and chemoselective amination substrate.5-Bromo-2-fluoropyrimidine undergoes chemoselective amination at the C-2 position (C-F bond) with no amination at the C-5 position (C-Br bond) in the presence of a Cu(II)/PTABS catalytic system.
For research use only. We do not sell to patients.
- Purity: 99.63%
- CAS No.: 62802-38-4
- Formula: C4H2BrFN2
- Molecular Weight:176.98
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
5-Bromo-2-fluoropyrimidine has a C-5 C-Br bond with a 37.45 kcal lower bond dissociation energy than its C-2 C-F bond[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 62802-38-4
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Appearance Solid
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Molecular Weight 176.98
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Formula C4H2BrFN2
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Color Off-white to light yellow
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SMILES
FC1=NC=C(Br)C=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (565.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6504 mL | 28.2518 mL | 56.5036 mL | 141.2589 mL |
| 5 mM | 1.1301 mL | 5.6504 mL | 11.3007 mL | 28.2518 mL | |
| 10 mM | 0.5650 mL | 2.8252 mL | 5.6504 mL | 14.1259 mL | |
| 15 mM | 0.3767 mL | 1.8835 mL | 3.7669 mL | 9.4173 mL | |
| 20 mM | 0.2825 mL | 1.4126 mL | 2.8252 mL | 7.0629 mL | |
| 25 mM | 0.2260 mL | 1.1301 mL | 2.2601 mL | 5.6504 mL | |
| 30 mM | 0.1883 mL | 0.9417 mL | 1.8835 mL | 4.7086 mL | |
| 40 mM | 0.1413 mL | 0.7063 mL | 1.4126 mL | 3.5315 mL | |
| 50 mM | 0.1130 mL | 0.5650 mL | 1.1301 mL | 2.8252 mL | |
| 60 mM | 0.0942 mL | 0.4709 mL | 0.9417 mL | 2.3543 mL | |
| 80 mM | 0.0706 mL | 0.3531 mL | 0.7063 mL | 1.7657 mL | |
| 100 mM | 0.0565 mL | 0.2825 mL | 0.5650 mL | 1.4126 mL |
5-Bromo-2-fluoropyrimidine Related Classifications
HY-W008137 Related Classifications
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