1 Result for "

C1-substituted

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "C1-substituted" in MCE Product Catalog:

Cat. No.: HY-175004
CAS No.: 1821339-88-1
Research Areas:  

Cancer

PBD dimer-4 (Compound 7) is a C1-subsitituted PBD dimer. PBD dimer-4 has high DNA-binding affinity, DNA cross-linking ability and potent cytotoxicity against MDA-MB-231 cells (IC50: 236 nM). PBD dimer-4 can be used as a payload of ADC Loncastuximab tesirine (HY-P99349) to treat several different cancer types [1].
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