11 Results for "

C1R

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "C1R" in MCE Product Catalog:

Cat. No.: HY-P5278
CAS No.: 130698-88-3
Target:  

Ser/Thr Protease

Research Areas:  

Others

Z-Gly-Arg-Thiobenzyl ester is a synthetic peptide substrate used to detect the cleavage activity of C1r. Z-Gly-Arg-Thiobenzyl ester can be cleaved by proteases such as C1r, and when used in combination with DTNB (HY-15915) , it enables colorimetric determination of protease activity, which can be applied to enzymological studies related to the complement system [1].
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Cat. No.: HY-E70391
Target:  

Others

Research Areas:  

Others

C1r Enzyme is the activated form of the C1r zymogen and serves as an activator of Cls [1] .
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Cat. No.: HY-P10827
CAS No.: 1356469-36-7
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

PIC1 PA, a 15 amino-acid peptide, is a potent PIC1 analog that inhibits classical pathway mediated complement activation. PIC1 PA functionally disrupts the C1s-C1r-C1r-C1s/MASPs interaction with collagen-like region (CLR) of C1q/MBL, respectively. PIC1 PA specifically binds to the CLR of C1q and bounds to purified C1q with a mean equilibrium dissociation constant (KD) of 33.3 nM [1].
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Cat. No.: HY-E70533
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C1r proenzyme, the native form of C1r enzyme, is an inactive zymogen until C1 is activated. C1r is activated when C1 binds to and is activated by antibodies bound to antigens (immune complexes) yielding C1r enzyme [1].
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Cat. No.: HY-P991629

Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

C1 Esterase Inhibitor (Human) is a C1 Esterase inhibitor derived from human plasma. C1 Esterase Inhibitor (Human), a glycoprotein, is a serum protease inhibitor (serpin) that binds covalently and inactivates C1r, C1s, and mannan-binding protein-associated proteases (MASPs). C1 Esterase Inhibitor (Human) has anti-inflammatory effects. C1 Esterase Inhibitor (Human) can be used to prevent angioedema attacks associated with hereditary angioedema [1] .
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Cat. No.: HY-RS01735
Research Areas:  

Others

C1R Human Pre-designed siRNA Set A contains three designed siRNAs for C1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24803
Research Areas:  

Others

C1r Rat Pre-designed siRNA Set A contains three designed siRNAs for C1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-E70534
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C1s Proenzyme, the native form of C1s enzyme, is an inactive zymogen until C1 is activated. C1 complex binds to and is activated by antigen-antibody complexes (immune complexes) yielding C1r enzyme. C1r enzyme in the C1 complex activates C1s proenzyme generating C1s enzyme [1].
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Cat. No.: HY-120765
CAS No.: 1304750-47-7
Research Areas:  

Cancer

BRD2879 is a potent IDH1-R132H inhibitor with IC50 values of 0.05, 2.5, >20, >20 µM for IDH1-R132H, IDH1-R132C, IDH1-WT, IDH2-R140Q, respectively. BRD2879 reduces (R)-2-hydroxyglutarate (R-2HG) levels [1].
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Cat. No.: HY-P88245
Synonyms: complement component 1; r subcomponent

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P88245A
Synonyms: complement component 1; r subcomponent

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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