1 Result for "

C5F2-HCB

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "C5F2-HCB" in MCE Product Catalog:

Cat. No.: HY-183844
CAS No.: 2792206-44-9
Research Areas:  

Cancer

C5F2-HCB is a CYP-mediated inhibitor of the biosynthesis of arachidonic acid epoxygenase product (±) 14,15-EET (HY-150084), with an IC50 of 3.1 μM. C5F2-HCB inhibits EET-driven oxidative phosphorylation (OXPHOS) associated with tumor hypoxia, converting an immunologically "cold" tumor microenvironment into a "hot" one. C5F2-HCB reverses the immune-excluded tumor microenvironment in ER +HER2 breast cancer allograft models. C5F2-HCB can be used in research related to ER +HER2 breast cancer .
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